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A beam of holy light reduces the vampire to nothing but dust.
The next few damage types are the hardest to imagine, because they don’t correspond with anything you’ll encounter in the real world. Radiant damage, for instance, refers to the burning power of holy light. While some might expect it to be effective against all unholy, undead monsters, it’s only the darkness-dwelling shadows that actually fear the light.
While the special damage types we’ve seen so far are mainly the purview of the party’s Wizard or [DnD Sorcerer](https://www.wargamer.com/dnd/sorcerer-subclasses-5e), radiant damage is more likely to be wielded by a 5e Cleric or Paladin. You’re unlikely to run into much that resists it, though if you’re waging war on heaven, there _are_ some strange celestial creatures that will only take half damage.